Research Article Open Access

Nanocrystalline Powders of Alkaline-Earth Phosphates as Precursors for Bioceramics

Parhi Purnendu1, A. Ramanan1 and Alok R. Ray1
  • 1 Indian Institute of Technology, India


Bone is a nanocomposite made of calcium phosphates and collagen. Collagen has a typical fibrous structure, with diameter ranging from 100 nm to 2 μm. It is suggested that calcium hydroxyapatite, Ca10(PO4)6(OH)2 in the size range 5-50 nm embedded in the collagen framework provides mechanical strength to bone. Among calcium phosphates, apatites are found to be the most suitable for bone regeneration due to its biocompatibility. A contemporary theme is to prepare nanocrystallites of alkaline-earth phosphates that can be employed as precursors for making novel bioceramics. In this paper, we present our attempts to prepare nano-sized particles of alkaline-earth hydroxyapatites, A10(PO4)6(OH)2 where A= Ca, Sr and Ba through a metathetical route. Our work involved the use of same reactants treated under different reaction conditions. While hydrothermal route yielded well-crystalline nanorods, microwave resulted in agglomerated hydroxyapatites and reverse micellear route gave low crystalline apatites with less agglomeration.

American Journal of Biochemistry and Biotechnology
Volume 2 No. 2, 2006, 61-65


Submitted On: 7 April 2006 Published On: 30 June 2006

How to Cite: Purnendu, P., Ramanan, A. & Ray, A. R. (2006). Nanocrystalline Powders of Alkaline-Earth Phosphates as Precursors for Bioceramics. American Journal of Biochemistry and Biotechnology, 2(2), 61-65.

  • 6 Citations



  • Alkaline-earth hydroxyapatite
  • metathesis
  • nanorods