@article {10.3844/ajbbsp.2006.61.65,
article_type = {journal},
title = {Nanocrystalline Powders of Alkaline-Earth Phosphates as Precursors for Bioceramics},
author = {Purnendu, Parhi and Ramanan, A. and Ray, Alok R.},
volume = {2},
number = {2},
year = {2006},
month = {Jun},
pages = {61-65},
doi = {10.3844/ajbbsp.2006.61.65},
url = {https://thescipub.com/abstract/ajbbsp.2006.61.65},
abstract = {Bone is a nanocomposite made of calcium phosphates and collagen. Collagen has a typical fibrous structure, with diameter ranging from 100 nm to 2 μm. It is suggested that calcium hydroxyapatite, Ca10(PO4)6(OH)2 in the size range 5-50 nm embedded in the collagen framework provides mechanical strength to bone. Among calcium phosphates, apatites are found to be the most suitable for bone regeneration due to its biocompatibility. A contemporary theme is to prepare nanocrystallites of alkaline-earth phosphates that can be employed as precursors for making novel bioceramics. In this paper, we present our attempts to prepare nano-sized particles of alkaline-earth hydroxyapatites, A10(PO4)6(OH)2 where A= Ca, Sr and Ba through a metathetical route. Our work involved the use of same reactants treated under different reaction conditions. While hydrothermal route yielded well-crystalline nanorods, microwave resulted in agglomerated hydroxyapatites and reverse micellear route gave low crystalline apatites with less agglomeration.},
journal = {American Journal of Biochemistry and Biotechnology},
publisher = {Science Publications}
}