American Journal of Pharmacology and Toxicology


American Journal of Pharmacology and Toxicology is a peer-reviewed open access journal that publishes original research / review articles on drug action in all the areas of pharmacology and toxicology including in vivo and in vitro metabolism, intracellular metabolism and intracellular regulation. Articles on effects of radiations, drug composition and properties, drug-drug interactions, pharmacokinetic and in vivo imaging of drug distribution are also encouraged. AJPT is a quarterly publication available both in print and online and is an authentic source of information on Pharmacology and Toxicology.

Current Issue

Safety Assessment of Indigenous Probiotic Strain Lactobacillus plantarum Dad-13 Isolated from Dadih Using Sprague Dawley Rats as a Model

Endang S Rahayu, Ilzamha H Rusdan, Armita Athennia, Rafli Z Kamil, Putrika C Pramesi, Yustinus Marsono, Tyas Utami and Jaka Widada
Published On : November 12, 2019

β-Naphthalene Incorporated Thiazole-5-Carboxamides/Thiazole -5- Ketones: Design, Synthesis and Anticonvulsant Screening against Two Seizure Models

Mohammed Faiz Arshad, Faisal Al-Otaibi, Gulam Mustafa, Saad Shousha and Abdulrahman Alshahrani
Volume : 14, Issue : 1 Pages : 27-37
Published On : August 29, 2019

Protective Effect of Curcumin Against Hepatic Toxicity Induced by Lithium Carbonate (Li2 Co3)

Gehan B.A. Youssef, Ahlam F. Hamoda, Rabab R. Elzoghby, Fatma Algendy and Shimaa A.E. Attwa
Volume : 14, Issue : 1 Pages : 17-26
Published On : July 31, 2019

Introducing a New Kit based on Modified Chromotropic Acid Method for Easy Determination of Methanol

Mohammad Reza Ghadirzadeh, Ali Rafizadeh, Akbar Fattahi, Seyed Davood Mirtorabi, Hajar Nazari and Melika Rafizadeh
Volume : 14, Issue : 1 Pages : 1-6
Published On : May 2, 2019

Progressive LDL Reduction to Very Low Levels Improves Dimeric Nitric Oxide Synthase, Nitric Oxide Bioavailability and Reduces Peroxynitrite in Endothelial Cells during Hyperglycemia

R. Preston Mason, Hazem Dawoud, Samuel C.R. Sherratt, Michael R. Wagner and Tadeusz Malinski
Volume : 14, Issue : 1 Pages : 7-16
Published On : May 2, 2019

Hypolipidemic Effects of Coenzyme Q10 in Experimentally Induced Hypercholesterolemic Model in Female Rats

Atef M. Al-Attar
Volume : 5, Issue : 1 Pages : 14-23
Downloads : 27470

Elucidating the Mechanism(s) of Hormesis at the Cellular Level: The Universal Cell Response

Paul S. Agutter
Volume : 3, Issue : 1 Pages : 100-110
Downloads : 19520

Plant Pectin: A Potential Source for Cancer Suppression

Suryakant K. Niture and Lubna Refai
Volume : 8, Issue : 1 Pages : 9-19
Downloads : 13683

Acute and Sub-acute Toxicity of Crataegus Aronia Syn. Azarolus (L.) Whole Plant Aqueous Extract in Wistar Rats

Abdullah S. Shatoor
Volume : 6, Issue : 2 Pages : 37-45
Downloads : 7306

The Health Risk of Formaldehyde to Human Beings

S. Norliana, A. S. Abdulamir, F. Abu Bakar and A. B. Salleh
Volume : 4, Issue : 3 Pages : 98-106
Downloads : 6558

Hypolipidemic Effects of Coenzyme Q10 in Experimentally Induced Hypercholesterolemic Model in Female Rats

Atef M. Al-Attar
Volume : 5, Issue : 1 Pages : 14-23
Views : 32512

Hepatoprotective Activity of Aqueous Ethanolic Extract of Chamomile capitula in Paracetamol Intoxicated Albino Rats

Ajay k. Gupta and Neelam Misra
Volume : 1, Issue : 1 Pages : 17-20
Views : 3016

Characterization of Nigella Sativa L. Essential Oil-Loaded Solid Lipid Nanoparticles

Nagi A. ALHaj, Mariana N. Shamsudin, Norfarrah M. Alipiah, Hana F. Zamri, Ahmad Bustamam, Siddig Ibrahim and Rasedee Abdullah
Volume : 5, Issue : 1 Pages : 52-57
Views : 2882

Aqueous Extract of Inonotus bliquus (Fr.) Pilat (Hymenochaetaceae) Significantly Inhibits the Growth of Sarcoma 180 by Inducing Apoptosis

Caifa Chen, Weifa Zheng, Xiaowen Gao and Xiaoyan Xiang
Volume : 2, Issue : 1 Pages : 10-17
Views : 2662

Uncommon Toxicologic Profile at Toxic Doses of CPI-613 (an Agent Selectively Alters Tumor Energy Metabolism) in Rats and Minipigs Reflects Novel Mechanism

King C. Lee, Claudia Maturo, Robert Shorr and Robert Rodriguez
Volume : 5, Issue : 4 Pages : 183-208
Views : 2266