Evaluation of the Role of Galanin Hormone and Biochemical Markers in Individuals with Hair Loss

Abstract

Hair loss is one of the problems that many people suffer from without knowing the real reason. Galanin is a neuropeptide closely involved in the modulation and inhibition of action potentials in neurons in the brain, spinal cord, and gut of humans. Therefore, we believe that it has a role in mineral absorption and hair loss. The aim of this study is to evaluate the level of galanin and its relationship with the levels of some minerals in the serum of people suffering from hair loss compared to healthy people. There are 60 patients who have lost their hair and 30 healthy people. This study discovered that the mean serum Galanin and Troponin level were higher in patients with hair loss compared to the control group. The findings were significant (p<0.001). As well as the Prolactin and FSH levels were higher in patients with hair loss compared to the control group. The findings were significant (p<0.001). While the TSH, Zn, Mg, Cu, Fe and Ca levels were lower in patient with hair loss compared with the control group, the result was significant (p<0.001). Also, the LH levels were increased in patient with hair loss compared with the control group, but the result was non-significant (p>0.05). The results of this study that increasing the level of Galanin and Troponin has an effect on hair loss, and also that the hormone prolactin affects the growth of hair follicles, as well as the hormone LH, which works to increase the level of testosterone, and this contributes to hair loss.