Research Article Open Access

Preparation of Low-Sugar Herbal Buccal Tablet and its Antioxidant Activity

Yuqing Wang1, Mingjie Sun1, Rui Xu1, Xuan Hu1, Yao Chen1, Jieru Zhang1, Hongfang Cai1, Gaixia Qu2, Xinyi Chen3, Yang Zhang1 and Dongxing Zhu1
  • 1 School of Biology and Food Engineering, Changshu Institute of Technology, Changshu, China
  • 2 Suzhou Yuankang Food Technology Co., Ltd, Suzhou, China
  • 3 School of Foreign Languages, Yili Normal University, Yining, China


In this study, in order to prepare a low-sugar Herbal Buccal Tablet (HBT), Response Surface Methodology (RSM) was used to optimize the formula of HBT. HBT was prepared by wet granulation and tableting process on the basis of formula optimization. The in vitro antioxidant activity, glycemic index and particle microstructure of HBT were evaluated. The results showed that the optimal formula for HBT was Siraitia grosvenorii fruit powder of 15%, canarium album fruit powder of 16%, lily bulb powder of 7.1%, erythritol of 55% and citric acid of 0.45%. HBT was prepared by adding 0.3% x glycosides, 5% Arabic gum, 1% magnesium stearate and 0.15% menthol on the basis of optimal formula. Under the optimal formula, the content of total flavonoids and saponins in HBT was 10.08±0.05 mg/g and 11.28±0.03 mg/g, respectively. HBT had an advantage over Commercial Sugar-Sweetened Confectionery (CSC) because of its higher antioxidant activity. The results showed that HBT may have the potential to become a traditional candy substitute in food industry due to its high content of active ingredients, low sugar content and good antioxidant activity in the future.

American Journal of Biochemistry and Biotechnology
Volume 18 No. 1, 2022, 87-99


Submitted On: 20 January 2022 Published On: 8 March 2022

How to Cite: Wang, Y., Sun, M., Xu, R., Hu, X., Chen, Y., Zhang, J., Cai, H., Qu, G., Chen, X., Zhang, Y. & Zhu, D. (2022). Preparation of Low-Sugar Herbal Buccal Tablet and its Antioxidant Activity. American Journal of Biochemistry and Biotechnology, 18(1), 87-99.

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  • Siraitia Grosvenorii Fruit
  • Siraitia Grosvenorii Fruit
  • Canarium Album Fruit
  • Lily Bulb
  • Herbal Buccal Tablet (HBT)
  • Antioxidant Activity