Literature Review Open Access

A Review on Effects of Bisphenol a on Reproductive, Endocrine Systems and its Influencing Mechanism

Ganghui Ye1, Liting Zheng2, Chang Meng1, Yuefeng Dong3, Hongyan Xu1 and Qinglu Wang4
  • 1 Qilu Medical University, China
  • 2 The First Dongguan Affiliated Hospital of Guangdong Medical Univerisity, China
  • 3 Binzhou Medical University, China
  • 4 Shandong Sport University, China

Abstract

Background and purpose: Bisphenol A (BPA) is a pervasive environmental toxicant with known adverse effects on human immune system and nervous system et al. Although, BPA is widely known to affect endocrine function in animals, the linkage between human exposure to BPA and human reproductive function is still not clearly clarified. Results: Systematic review of all articles about BPA and human reproductive function identified in SCOPUS and PubMed. Literature was summarized in narrative form and results are presented per category. Some observational surveys investigating the relationship between BPA exposure and human reproductive and/or endocrine function are inconsistent. Conclusion: Our review integrates the studies of BPA on reproductive and/or endocrine system in recent years, mainly explains the effects of BPA on these systems and provides the basis for subsequent studies on BPA.

American Journal of Biochemistry and Biotechnology
Volume 17 No. 4, 2021, 408-422

DOI: https://doi.org/10.3844/ajbbsp.2021.408.422

Submitted On: 28 May 2021 Published On: 3 December 2021

How to Cite: Ye, G., Zheng, L., Meng, C., Dong, Y., Xu, H. & Wang, Q. (2021). A Review on Effects of Bisphenol a on Reproductive, Endocrine Systems and its Influencing Mechanism. American Journal of Biochemistry and Biotechnology, 17(4), 408-422. https://doi.org/10.3844/ajbbsp.2021.408.422

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Keywords

  • Bisphenol A
  • Endocrine Disruptor
  • Reproductive Hormone
  • Semen Quality