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The Phytol-rich Essential Oil from Fresh Medicago hispida Exerts Significant Inhibitory Activity against Escherichia coli

Lixue Zheng1, Leijie Ben1, Zhumei Cui1, Qian Fu1, Limei Wang1, Bin Qi1 and Yang Zhang1
  • 1 Changshu Institute of Technology, China

Abstract

Medicago hispida is one of the most widely distributed and commonly cultivated plants of the genus Medicago in China. It is mainly consumed as a vegetable. In this paper, the extraction, chemical composition and antimicrobial potential of the essential oil from fresh M. hispida (EOFMH) were conducted and evaluated for the first time. The extraction yield of EOFMH was found to be 0.27% and 27 compounds were identified in EOFMH by gas chromatography-mass spectrometer (GC-MS) with the highest level of phytol, accounting for 48.8%. EOFMH exhibited certain inhibitory effects against Staphylococcus aureus, Escherichia coli, Candida albicans, Bacillus pumilus and Bacillus subtilis, particularly its antibacterial activity against E. coli was equivalent to that of chloramphenicol. Results obtained from present work provided strong evidence that EOFMH could be considered as a phytol-rich natural product and a new source of nature-based antibacterial agent to be applied in industry.

American Journal of Biochemistry and Biotechnology
Volume 15 No. 4, 2019, 270-274

DOI: https://doi.org/10.3844/ajbbsp.2019.270.274

Submitted On: 2 October 2019 Published On: 28 December 2019

How to Cite: Zheng, L., Ben, L., Cui, Z., Fu, Q., Wang, L., Qi, B. & Zhang, Y. (2019). The Phytol-rich Essential Oil from Fresh Medicago hispida Exerts Significant Inhibitory Activity against Escherichia coli. American Journal of Biochemistry and Biotechnology, 15(4), 270-274. https://doi.org/10.3844/ajbbsp.2019.270.274

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Keywords

  • Medicago hispida
  • Essential Oil
  • Phytol
  • Antibacterial Activity