Review Article Open Access

The Progress of BMP4 on the Role of Ocular Development and Eye Diseases

Liang Jiaming1, Wang Qian1, Liu Xiaohe2, Wang Shurong1 and Zhang Yan1
  • 1 The 2nd Teaching Hospital of Jilin University, China
  • 2 Norman Bethune Health Science of Jilin University, China

Abstract

Bone morphogenetic protein belongs to the transforming growth factor beta superfamily, is a unique ectopic cartilage and bone inducing activity of acidic protein. As one of the members of BMPs family, the formation and development of BMP4 in many organizations. In ocular tissue, BMP4 not only promotes the differentiation and development of different eye cells, but also plays an important role in ocular diseases. In this study, the recent advances in the study of BMP4 in ocular tissues are summarized and the function of BMP4 in different developmental stages of eye is briefly reviewed.

American Journal of Biochemistry and Biotechnology
Volume 13 No. 2, 2017, 58-62

DOI: https://doi.org/10.3844/ajbbsp.2017.58.62

Submitted On: 7 March 2017 Published On: 5 April 2017

How to Cite: Jiaming, L., Qian, W., Xiaohe, L., Shurong, W. & Yan, Z. (2017). The Progress of BMP4 on the Role of Ocular Development and Eye Diseases. American Journal of Biochemistry and Biotechnology, 13(2), 58-62. https://doi.org/10.3844/ajbbsp.2017.58.62

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Keywords

  • Bone Morphogenetic Protein 4
  • Eye
  • Regulation
  • Cell