Research Article Open Access

Nano-Diamond Hybrid Materials for Structural Biomedical Application

Raffaella Aversa1, Relly Victoria V. Petrescu2, Antonio Apicella1 and Florian Ion T. Petrescu2
  • 1 University of Campania, Italy
  • 2 Bucharest Polytechnic University, Romania

Abstract

The development of new diamond based bio-mechanically active hybrid nano-structured scaffolds for cartilage cells tissue engineering are proposed in this study. Innovative tissue engineering biomimetic materials based on hydrogel have shown attractive physical, biological and mechanical properties in several biomedical applications. A highly biocompatible novel hybrid material based on nanodiamonds and hydrophilic poly-(hydroxyl-ethyl-methacrylate) (pHEMA) is proposed. The aim of this paper is to describe the chemical and analytical procedures for the preparation of nanofilled hybrid composites possessing biomimetic, osteoconductive and osteoinductivity properties that can be useful in the design of bio-mechanically active innovative bone scaffolding systems for stem cell differentiation and growth. A more rigid and rubber transparent hybrid nano-composites are predicted to posses improved mechanical strength overwhelming one of the major weaknesses of hydrogels, which is due their poor mechanical characteristics, for applications in biomedical structural application.

American Journal of Biochemistry and Biotechnology
Volume 13 No. 1, 2017, 34-41

DOI: https://doi.org/10.3844/ajbbsp.2017.34.41

Submitted On: 2 February 2017 Published On: 9 March 2017

How to Cite: Aversa, R., Petrescu, R. V. V., Apicella, A. & Petrescu, F. I. T. (2017). Nano-Diamond Hybrid Materials for Structural Biomedical Application. American Journal of Biochemistry and Biotechnology, 13(1), 34-41. https://doi.org/10.3844/ajbbsp.2017.34.41

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Keywords

  • Biomaterials
  • Bioactive Scaffolds
  • Bioengineering
  • Biomedical