Research Article Open Access

Physiological Active Substance Changes of Soybean Curd Residue Fermented by Preussia aemulans and its Bioactivity

Yiting Li1, Shili Meng2, Min Shi2 and Zhenya Zhang2
  • 1 Tianjin University of Science and Technology, China
  • 2 University of Tsukuba, Japan

Abstract

A new species of fungus Preussia aemulans isolated from the Cordyceps sinensis fruiting body was cultured by soybean curd residue using solid-state fermentation method. The content of polysaccharide, amino acid, protein, phenolics and nucleoside were massively improved under the optimum conditions, including 10% adding dosage of glucose, 3% adding dosage of beef extract, 15 days of fermentation time. The crude Polysaccharide (CPS) fraction indicated significant immunomodulatory activity on macrophage RAW 264.7 cells and the Ethyl Acetate Extract (EAE) fraction revealed the moderate anti-proliferation ability on human colon cancer cell DLD-1 at high concentration. Both of CPS and EAE showed excellent antioxidant activities properties. The results were demonstrated that the fermented Soybean Curd Residue (SCR) could be utilized as nontoxic, safe and functional food, food additive and feed.

American Journal of Biochemistry and Biotechnology
Volume 12 No. 1, 2016, 26-35

DOI: https://doi.org/10.3844/ajbbsp.2016.26.35

Submitted On: 19 October 2015 Published On: 6 January 2016

How to Cite: Li, Y., Meng, S., Shi, M. & Zhang, Z. (2016). Physiological Active Substance Changes of Soybean Curd Residue Fermented by Preussia aemulans and its Bioactivity. American Journal of Biochemistry and Biotechnology, 12(1), 26-35. https://doi.org/10.3844/ajbbsp.2016.26.35

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Keywords

  • Soybean Curd Residue
  • Preussia aemulans
  • Antioxidative Property
  • Immunomodulatory Activity
  • Anti-Tumor Activity