Research Article Open Access

Detection of Cancer Biomarkers with Nanotechnology

Lei Zhang1, Dan Lv2, Weijun Su1, Yanhua Liu1, Yanan Chen1 and Rong Xiang1
  • 1 Nankai University, China
  • 2 University of California, United States


Early detection of cancer biomarkers with high precision is critically important for cancer therapy. A variety of sensors based on different nanostructured materials have attracted intensive research interest due to their potential for highly sensitive and selective detection of cancer biomarkers. This review covers the use of a variety of nanostructured materials, including carbon nanotubes, silicon nanowires, gold nanoparticles and quantum dots, in the fabrication of sensors. Emphases are placed on how the detection systems work and what detection limits can be achieved. Some assays described in this review outperform established methods for cancer biomarker detection. It is highly promising that these sensors would soon move into commercial-scale production and find routine use in hospitals.

American Journal of Biochemistry and Biotechnology
Volume 9 No. 1, 2013, 71-89


Submitted On: 31 October 2012 Published On: 18 March 2013

How to Cite: Zhang, L., Lv, D., Su, W., Liu, Y., Chen, Y. & Xiang, R. (2013). Detection of Cancer Biomarkers with Nanotechnology. American Journal of Biochemistry and Biotechnology, 9(1), 71-89.

  • 35 Citations



  • Cancer
  • Biomarker
  • Nanostructured Materials
  • Sensor
  • Immunoassay