Research Article Open Access

The Role of Neurodevelopmental Genes in Infectious Etiology of Autism

S. Hossein Fatemi1
  • 1 University of Minnesota, United States

Abstract

Autism is a neurodevelopmental disorder with both genetic and environmental etiologies. Prenatal infections may play a role in evolution of autism. Experimental evidence shows human influenza viral infection in pregnancy leads to significant deleterious effects in brain structure and function in the developing mouse progeny. Several brain genes of interest in this animal model are also involved in the pathology of autism. The roles of these genes in brain development are discussed in this review.

American Journal of Biochemistry and Biotechnology
Volume 4 No. 2, 2008, 177-182

DOI: https://doi.org/10.3844/ajbbsp.2008.177.182

Submitted On: 19 July 2007 Published On: 30 June 2008

How to Cite: Fatemi, S. H. (2008). The Role of Neurodevelopmental Genes in Infectious Etiology of Autism. American Journal of Biochemistry and Biotechnology, 4(2), 177-182. https://doi.org/10.3844/ajbbsp.2008.177.182

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Keywords

  • Autism
  • influenza
  • viral model
  • brain genes
  • mouse