OnLine Journal of Biological Sciences

Strategies of Tuberculosis–HIV Vaccines Design using Immunoinformatic Approach

Ani Fatonah, Ig. Satrio Wicaksono and Usman Sumo Friend Tambunan

DOI : 10.3844/ojbsci.2019.110.116

OnLine Journal of Biological Sciences

Volume 19, Issue 2

Pages 110-116

Abstract

Tuberculosis is amongst the highest cause death worldwide. According to WHO, an estimated of more than a million people fell ill with Tuberculosis (TB) in 2016. The resistances of the M. tuberculosis (MTb) bacteria make drugs, not that useful in battle with TB. Vaccination is a better choice to avoid the worst cases of TB. The resistance possessed by MTb bacteria with some of the drugs reported creates its challenge to reduce the high rate of TB related death. One of the concerns is the high mortality rate due to TB associated with HIV. However, there’s still no effective vaccine for Tuberculosis-Human Immunodeficiency Virus (TB-HIV). Vaccines for Tuberculosis-HIV even on the way of progress to get the demanding the mutation of the bacteria and challenging scientists to get the right vaccines for this disease. Immunoinformatic is one of the approaches that can speed up the making of the vaccine.

Copyright

© 2019 Ani Fatonah, Ig. Satrio Wicaksono and Usman Sumo Friend Tambunan. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.