Antibacterial and Anti-Quorum Sensing Activities of Selected Italian Honeys against Antibiotic-Resistant Pathogens
Marco Fidaleo, Roberto Lavecchia and Antonio Zuorro
DOI : 10.3844/ojbsci.2015.236.243
OnLine Journal of Biological Sciences
Volume 15, Issue 4
Three nectar honeys (eucalyptus, thyme and forest) and two honeydew honeys (fir and Metcalfa) from Italy were tested for their antibacterial activity against pathogens commonly associated with wound and burn infections, including Methicillin-Resistant Staphylococcus Aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE) and Vancomycin-Resistant Enterococcus Faecalis (VREF). All honeys showed bactericidal activity against the microorganisms used, with honeydew honeys being the most effective. They also inhibited, in a dose-dependent manner, violacein production in Chromobacterium violaceum, thus demonstrating their ability to affect quorum sensing-regulated biofilm formation. Overall, the results obtained suggest that the honeys examined may have potential for developing natural antimicrobial compositions or dressings for the treatment of infected wounds or burns.
© 2015 Marco Fidaleo, Roberto Lavecchia and Antonio Zuorro. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.