American Journal of Biochemistry and Biotechnology

Identification of Major Cultivable Aerobic Bacteria in the Oral Cavity of Malaysian Subjects

Koshy Philip, Wuen Yew Teoh, Sekaran Muniandy and Hashim Yaakob

DOI : 10.3844/ajbbsp.2008.367.370

American Journal of Biochemistry and Biotechnology

Volume 4, Issue 4

Pages 367-370


Culture dependent and culture independent methods have shown that about 600 species of bacteria inhabit the human oral cavity. While some oral microorganisms have a direct link to dental caries, periodontal disease and halitosis, opportunistic pathogens may be responsible for systemic diseases such as bacterial endocarditis, aspiration pneumonia, osteomyelitis in children, preterm low birth weight, coronary heart disease and cerebral infarction (or stroke). This study employs bacterial 16S rDNA sequences to rapidly identify the major cultivable aerobic bacteria in the oral cavity of Malaysian subjects. The data obtained shows that the oral cavity of healthy volunteers contains a number of potentially pathogenic organisms including Streptococcus pneumoniae and Staphylococcus aureus. The need to profile and characterize these microorganisms using rapid detection methods can go a long way in developing future management strategies in clinical setting to enhance oral health in the Malaysian population.


© 2008 Koshy Philip, Wuen Yew Teoh, Sekaran Muniandy and Hashim Yaakob. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.