American Journal of Pharmacology and Toxicology

Description

American Journal of Pharmacology and Toxicology is a peer-reviewed open access journal that publishes original research / review articles on drug action in all the areas of pharmacology and toxicology including in vivo and in vitro metabolism, intracellular metabolism and intracellular regulation. Articles on effects of radiations, drug composition and properties, drug-drug interactions, pharmacokinetic and in vivo imaging of drug distribution are also encouraged. AJPT is a quarterly publication available both in print and online and is an authentic source of information on Pharmacology and Toxicology.

Letter from the Editor in Chief

Pharmacology and toxicology have evolved to scientific disciplines from human activities almost 7000 years old. It has always been a human attempt to identify new therapeutics from natural product sources, while learning their limitation and side effects the hard way. They became recognized disciplines only at the beginning of the 19th century, with the increasing tendency to explore the action of drugs and natural extracts on tissue and organ functions, as well as their use as tools to understand the origin of diseases.

From those times, the exponential increase of understanding of receptor and targets, from organ to cellular to nuclear levels has driven the research in these fields. With the advent of molecular biology and the use of technology platforms, pharmacology and toxicology seemed to have lost their role of integrative disciplines. Most recently, the need to go back to “the big picture” has characterize a new attention waive to pharmacology and toxicology, with the creation of disciplines, such as quantitative and system pharmacology or translational pharmacology, which encase concepts that have always been the basis of “classical” pharmacology and toxicology.

In these new times, I am excited to join American Journal of Pharmacology and Toxicology (AJPT) as Editor in Chief. AJPT was launched as open access journal in March 2006 and meanwhile has become truly international, publishing original articles and reviews from all over the world including countries from Africa, Asia, Europe, and America.

My mission is to promote AJPT as a key title in the field, publishing papers of outstanding quality covering all the multifaceted aspects of pharmacology and toxicology, from target identification to pharmaco- and toxico-kinetics, from drug-drug interaction to non-clinical regulatory and human toxicology and, to keep faith to the origins of the discipline, to the actions of natural extracts. My hope is that AJPT will continue to grow and to provide excelling information to everybody in these fields.

I like to take this opportunity to invite scientists and clinicians from all over the world to submit their manuscripts to AJPT and to contribute in this way to spread the knowledge in pharmacology and toxicology.

  • Tiziana Adage
    Editor in Chief
    American Journal of Pharmacology and Toxicology

Current Issue

Vascular Endothelial Growth Factor: An Overview Across Multiple Disease Conditions

Pages : 1-12

DOI : 10.3844/ajptsp.2015.1.12

Published On : May 6, 2015

Prescription Pattern of Anti-Hypertensive Drugs in Adherence to JNC- 7 Guidelines

Pages : 27-31

DOI : 10.3844/ajptsp.2015.27.31

Published On : June 2, 2015

Effects of Recombinant Toxin Phospholipase D in Cardiac Muscle of Rats

Pages : 32-36

DOI : 10.3844/ajptsp.2015.32.36

Published On : June 2, 2015



Analgesic and Anti-inflammatory Activity of Euphorbia antiquorum Linn

Banibrata Das, Samina Alam, Rajib Bhattacharjee and Biplab Kumar Das
Published On : August 27, 2015


Prescription Pattern of Anti-Hypertensive Drugs in Adherence to JNC- 7 Guidelines

Krishna Murti, M. Arif Khan, Akalanka Dey, Manoj Kumar Sethi, Pradeep Das and Krishna Pandey
Volume : 10, Issue : 1 Pages : 27-31
Published On : June 2, 2015


Effects of Recombinant Toxin Phospholipase D in Cardiac Muscle of Rats

Joao Victor Capelli Peixoto, Fernando Augusto Lavezzo Dias, Carlos Estevan Nolf Damiani, Ilana Kassouf Silva, Silvio Sanches Veiga, Julio Cesar Francisco and Rosalvo Tadeu Hochmueller Fogaça
Volume : 10, Issue : 1 Pages : 32-36
Published On : June 2, 2015


Selected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume Parenterals

Mohabbat Ullah
Volume : 10, Issue : 1 Pages : 13-26
Published On : May 27, 2015


Vascular Endothelial Growth Factor: An Overview Across Multiple Disease Conditions

Miriam Canavese
Volume : 10, Issue : 1 Pages : 1-12
Published On : May 6, 2015


Tamoxifen Drug Loading Solid Lipid Nanoparticles Prepared by Hot High Pressure Homogenization Techniques

Nagi A. ALHaj, Rasedee Abdullah, Siddig Ibrahim and Ahmad Bustamam
Volume : 3, Issue : 3 Pages : 219-224
Cites : 29


An Analysis of the Creatine Kinase Isoenzyme and Cardiac Troponin T Levels in a Polymyositis Patient

R. M. Golding, L. G.F. Giles and E. M. Sokoya
Volume : 4, Issue : 1 Pages : 1-7
Cites : 26



Volume : 3, Issue : 1 Pages : 69-76
Cites : 23


Cardioprotective Effect of Cucumis trigonus Roxb on Isoproterenol-Induced Myocardial Infarction in Rat

B. S. Thippeswamy, S. P. Thakker, S. Tubachi, G. A. Kalyani, M. K. Netra, U. Patil, S. Desai, C. C. Gavimath and V. P. Veerapur
Volume : 4, Issue : 2 Pages : 29-37
Cites : 21


Anti-Ulcer (Ulcer-Preventive) Activity of Ficus arnottiana Miq. (Moraceae) Leaf Methanolic Extract

Marslin Gregory, K. P. Vithalrao, G. Franklin and V. Kalaichelavan
Volume : 4, Issue : 3 Pages : 89-93
Cites : 20


Hypolipidemic Effects of Coenzyme Q10 in Experimentally Induced Hypercholesterolemic Model in Female Rats

Atef M. Al-Attar
Volume : 5, Issue : 1 Pages : 14-23
Downloads : 26319


PLANT PECTIN: A POTENTIAL SOURCE FOR CANCER SUPPRESSION

Suryakant K. Niture and Lubna Refai
Volume : 8, Issue : 1 Pages : 9-19
Downloads : 11599


Acute and Sub-acute Toxicity of Crataegus Aronia Syn. Azarolus (L.) Whole Plant Aqueous Extract in Wistar Rats

Abdullah S. Shatoor
Volume : 6, Issue : 2 Pages : 37-45
Downloads : 5932


In Vitro and In Vivo Anticancer Activity of Bacoside A from Whole Plant of Bacopa Monnieiri (Linn)

N. S. Prakash, R. Sundaram and S. K. Mitra
Volume : 6, Issue : 1 Pages : 11-19
Downloads : 4299


Tamoxifen Drug Loading Solid Lipid Nanoparticles Prepared by Hot High Pressure Homogenization Techniques

Nagi A. ALHaj, Rasedee Abdullah, Siddig Ibrahim and Ahmad Bustamam
Volume : 3, Issue : 3 Pages : 219-224
Downloads : 3118


Hypolipidemic Effects of Coenzyme Q10 in Experimentally Induced Hypercholesterolemic Model in Female Rats

Atef M. Al-Attar
Volume : 5, Issue : 1 Pages : 14-23
Views : 30189


Characterization of Nigella Sativa L. Essential Oil-Loaded Solid Lipid Nanoparticles

Nagi A. ALHaj, Mariana N. Shamsudin, Norfarrah M. Alipiah, Hana F. Zamri, Ahmad Bustamam, Siddig Ibrahim and Rasedee Abdullah
Volume : 5, Issue : 1 Pages : 52-57
Views : 1309


Uncommon Toxicologic Profile at Toxic Doses of CPI-613 (an Agent Selectively Alters Tumor Energy Metabolism) in Rats and Minipigs Reflects Novel Mechanism

Claudia Maturo, King C. Lee, Robert Rodriguez and Robert Shorr
Volume : 5, Issue : 4 Pages : 183-208
Views : 1217


Hepatoprotective Activity of Aqueous Ethanolic Extract of Chamomile capitula in Paracetamol Intoxicated Albino Rats

Ajay k. Gupta and Neelam Misra
Volume : 1, Issue : 1 Pages : 17-20
Views : 1197


Cytoprotective Effect of UlGen, a Polyherbal Formulation against Physical and Chemical Factor Induced Gastric Ulcers in Wister Albino Rats

T. S. Muralidhar, Anna Balaji, Chinmay Bandopadhyay and S. L. Shantha
Volume : 4, Issue : 3 Pages : 80-84
Views : 984