Omicron SARS Co-V2 Sub Variants BA.2 and BA.3 have Lower Free Binding Energy than BA.1
- 1 Department of Consultant, Private Academic Consultant, Thailand
- 2 Department of Community Medicine, Dy Patil University, India
Abstract
COVID-19 is currently a major global public health concern. The newest dangerous type, Omicron, comes in late 2021 and spreads quickly from Africa. There have already been new omicron subvariants discovered. Mutations inside the molecular structure of omicron subvariant induce intriguing molecular changes. The authors undertook a study to examine the effects of mutations in important COVID-19 omicron subvariants, including BA.1, BA.2, and BA.3, based on free binding energy alterations. According to molecular study findings, each studied subvariant has a different free binding energy. The BA.3 has undergone the most changes. As a result, the binding of ACE-2 may be affected. This suggests that the new subvariant may be linked to a higher likelihood of transmission.
DOI: https://doi.org/10.3844/ajassp.2022.105.108
Copyright: © 2022 Rujittika Mungmunpuntipantip and Viroj Wiwanitkit. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Omicron
- Variant
- Subvariant
- COVID-19
- Binding Energy