Speed of Sound and Apparent Molal Volume Approach to Study the Ion-Solvent Interactions in Pharmaceutically Important Liquid Systems
- 1 Department of Chemistry, Rajiv Gandhi Institute of Technology (VTU), Bangalore – 32, India
- 2 Department of Chemistry, East Point College of Engineering and Technology (VTU), Bangalore –49, India
Abstract
Presence of zinc ion and lactose in different pharmaceutical compositions have been inspired to investigate the ion-solvation and related interactions among the components in solution media. This study has been carried out by the measurements of ultrasonic velocity, viscosity and density for the binary solutions of zinc sulphate (ZnSO4) in lactose-water mixed solvent systems at 303.15, 308.15, 313.15 K temperature and at atmospheric pressure. Different thermo-acoustic parameters such as isentropic compressibility, apparent molal volume, solvation number, free volume, internal pressure etc., have been evaluated from the measured values. All these parameters have been analyzed in the light of molecular interactions from their variations against concentration as well as temperature. Presence of ion-solvation and structure promoting nature of solute are the major findings in the present investigation. Besides, it also reveals that the ion-solvation decreases as the temperature increases.
DOI: https://doi.org/10.3844/ajassp.2020.56.68
Copyright: © 2020 D.N. Ganesh, Vinay S. Bhat and Susmita Kamila. This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Solute-Solvent Interaction
- Ion-Solvation
- Thermo-Acoustic Parameters
- Apparent Molal Compressibility