Research Article Open Access

Relation between Autoimmunity Chronic Urticaria and the Levels of Plasma Prothrombin F1+2

Liu Xiaoming, Sheng Wanxiang, Ahmad T. Khalaf, Song Jiquan and Tan Jinquan

Abstract

A number of recent epidemiologic and experimental studies have enhanced our knowledge of the etiology and pathogenesis of chronic urticaria (CU), a disease that imposes profound impairment on patient's quality of life. Our study was performed to explore the relation between autoimmunity (CU) and the levels of plasma prothrombin F1+2. Thirty four (CU) patients with positive autologous serum skin test (APST) their F1+2 were measured by ELISA at pre and post therapy. The levels of F1+2 in autoimmunity (CU) patients have been decreased obviously after treatment (3.34±2.87vs 0.94±0.58, p<0.001). Before treatment, the levels of treatment group was significantly higher than that of control group (3.34±2.87vs 0.72±0.36,p<0.001). After treatment, they have no significant difference (0.94±0.58vs 0.72±0.36, p>0.05).

American Journal of Applied Sciences
Volume 4 No. 12, 2007, 965-969

DOI: https://doi.org/10.3844/ajassp.2007.965.969

Submitted On: 1 June 2007 Published On: 31 December 2007

How to Cite: Xiaoming, L., Wanxiang, S., Khalaf, A. T., Jiquan, S. & Jinquan, T. (2007). Relation between Autoimmunity Chronic Urticaria and the Levels of Plasma Prothrombin F1+2 . American Journal of Applied Sciences, 4(12), 965-969. https://doi.org/10.3844/ajassp.2007.965.969

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Keywords

  • chronic urticaria
  • F1+2
  • Loratadine
  • dipyridamole