American Journal of Applied Sciences

Relation between Autoimmunity Chronic Urticaria and the Levels of Plasma Prothrombin F1+2

Liu Xiaoming, Sheng Wanxiang, Ahmad T. Khalaf, Song Jiquan and Tan Jinquan

DOI : 10.3844/ajassp.2007.965.969

American Journal of Applied Sciences

Volume 4, Issue 12

Pages 965-969


A number of recent epidemiologic and experimental studies have enhanced our knowledge of the etiology and pathogenesis of chronic urticaria (CU), a disease that imposes profound impairment on patient’s quality of life. Our study was performed to explore the relation between autoimmunity (CU) and the levels of plasma prothrombin F1+2. Thirty four (CU) patients with positive autologous serum skin test (APST) their F1+2 were measured by ELISA at pre and post therapy. The levels of F1+2 in autoimmunity (CU) patients have been decreased obviously after treatment (3.34±2.87vs 0.94±0.58, p<0.001). Before treatment, the levels of treatment group was significantly higher than that of control group (3.34±2.87vs 0.72±0.36,p<0.001). After treatment, they have no significant difference (0.94±0.58vs 0.72±0.36, p>0.05).


© 2007 Liu Xiaoming, Sheng Wanxiang, Ahmad T. Khalaf, Song Jiquan and Tan Jinquan. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.