American Journal of Biochemistry and Biotechnology

Nano-Diamond Hybrid Materials for Structural Biomedical Application

Raffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella and Florian Ion T. Petrescu

DOI : 10.3844/ajbbsp.2017.34.41

American Journal of Biochemistry and Biotechnology

Volume 13, Issue 1

Pages 34-41

Abstract

The development of new diamond based bio-mechanically active hybrid nano-structured scaffolds for cartilage cells tissue engineering are proposed in this study. Innovative tissue engineering biomimetic materials based on hydrogel have shown attractive physical, biological and mechanical properties in several biomedical applications. A highly biocompatible novel hybrid material based on nanodiamonds and hydrophilic poly-(hydroxyl-ethyl-methacrylate) (pHEMA) is proposed. The aim of this paper is to describe the chemical and analytical procedures for the preparation of nanofilled hybrid composites possessing biomimetic, osteoconductive and osteoinductivity properties that can be useful in the design of bio-mechanically active innovative bone scaffolding systems for stem cell differentiation and growth. A more rigid and rubber transparent hybrid nano-composites are predicted to posses improved mechanical strength overwhelming one of the major weaknesses of hydrogels, which is due their poor mechanical characteristics, for applications in biomedical structural application.

Copyright

© 2017 Raffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella and Florian Ion T. Petrescu. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.