Review Article Open Access

Coenzyme Q10 and its Effective Sources

Hamideh Vaghari1, Roholah Vaghari2, Hoda Jafarizadeh-Malmiri1 and Aydin Berenjian3
  • 1 Sahand University of Technology, Iran
  • 2 Shahid Beheshti University, Iran
  • 3 University of Waikato, New Zealand
American Journal of Biochemistry and Biotechnology
Volume 12 No. 4, 2016, 214-219

DOI: https://doi.org/10.3844/ajbbsp.2016.214.219

Submitted On: 8 June 2016 Published On: 10 October 2016

How to Cite: Vaghari, H., Vaghari, R., Jafarizadeh-Malmiri, H. & Berenjian, A. (2016). Coenzyme Q10 and its Effective Sources. American Journal of Biochemistry and Biotechnology, 12(4), 214-219. https://doi.org/10.3844/ajbbsp.2016.214.219

Abstract

Coenzyme Q10 (2,3-dimethoxy, 5-methyl, 6-decaprenyl benzoquinone, CoQ10) is naturally present in many organisms. It has key roles in several biochemical pathways. CoQ10, as an electron and proton carrier for energy coupling leads to Adenosine Triphosphate (ATP) formation. Furthermore, in medicine, the pharmacological use of CoQ10 has attracted more attention due to its benefits in treating cardiovascular and degenerative neurologic diseases. CoQ10 can be produced by chemical synthesis, extraction from biological tissues and microbial fermentation. It is found in plants such as soya bean, peanut, palm oil and litchi pericarp and in animals such as pelagic fish, beef and pork hearts. Various analytical methods have been published for the extraction and analysis of CoQ10 from different matrices. Biological production of CoQ10 offers an environmentally benign option based on the enzymatic catalysis at the cellular level. Moreover, this process due to ease of control and low production costs offers more advantages over the existing technologies.

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Keywords

  • CoQ10
  • Adenosine Triphosphate (ATP)
  • Mitochondrial Enzymes
  • Extraction
  • Microbial Fermentation