@article {10.3844/ojbsci.2022.214.222,
article_type = {journal},
title = {Adult Patients with Aphallia: Were they Fertile?},
author = {Sisca, Eni Maria and Pakpahan, Cennikon and Rezano, Andri and Margiana, Ria and Agustinus, Agustinus and Tanojo, Tjahjo Djojo},
volume = {22},
number = {2},
year = {2022},
month = {May},
pages = {214-222},
doi = {10.3844/ojbsci.2022.214.222},
url = {https://thescipub.com/abstract/ojbsci.2022.214.222},
abstract = {Adult male genotype and phenotype with aphallia are men born
without a penis. The effectiveness of male sex assignment or female sex
reassignment as a treatment for aphallia has been debated. The study's
goal was to address the gonadal existence and supporting investigation
related to the reproductive health care of reported cases of aphallia
patients such as karyotyping, physical examination, semen analysis,
hormone reproduction level, sperm retrieval, radiological investigation
type of intervention. In this narrative review, data were obtained from
Pubmed and Google Scholar that contains keywords “absence penis",
"penile agenesis”, “phalloplasty” “fertility function”. We excluded
pediatric patients with aphallia or adult patients with aphallia that reassignments to be female. Only five of the case reports were adult patients
with aphallia that reported their fertility function and remains the gonadal
existence. All samples have fertility potential disregard their aphallia
based on primary testicular function, semen analysis, hormonal profile
radiological investigation. Radiology supporting to the investigation of
fertility function has aimed to detect genitourinary anomaly related to the
site of urinary meatus associated with death rate. Four patients showed
post sphincteric meatus urinary and one patient was presphincteric
meatus urinary. Gonadal existence is addressed in the case report. This
report suggested that sex assignment on aphallia patients should be
considered based on the gonadal existence because even though they do
not have a penis, they can have children through assisted reproductive
technology provided that their phenotype and genotype are matched},
journal = {OnLine Journal of Biological Sciences},
publisher = {Science Publications}
}