@article {10.3844/ojbsci.2021.334.345,
article_type = {journal},
title = {Marking of Meat Productivity Features in Pairs of bGH, bGHR and bIGF-1 Polymorphic Genes in Aberdeen-Angus Cattle},
author = {Dushayeva, Laura Zhanedilovna and Nametov, Askar Myrzahmetovich and Beishova, Indira Saltanovna and Belaya, Alena Valentinovna and Ulyanova, Tatyana Vladimirovna and Kovalchuk, Alexandr Mikhailovich and Tagirov, Khamit Kharisovich and Yuldashbayev, Yusupzhan Artykovich},
volume = {21},
number = {2},
year = {2021},
month = {Jun},
pages = {334-345},
doi = {10.3844/ojbsci.2021.334.345},
url = {https://thescipub.com/abstract/ojbsci.2021.334.345},
abstract = {The purpose of the study is to identify paired combinations associated with meat productivity in Aberdeen-Angus cattle for the genes of the somatotropin cascade (growth hormone bGH, growth hormone receptor bGHR, insulin-like growth factor-1 bIGF-1). The determination of animal genotypes was carried out by PCR-RFLP. Results of statistical processing was carried out using the software capabilities of "Microsoft Excel 2010" and "Statistica 6.0". Paired combinations study of bGH, bGHR and bIGF-1 somatotropin cascade revealed marking diplotype polymorphic genes associated with signs of meat productivity and allowing for a comprehensive assessment of the Aberdeen-Angus cattle genetic potential in the postnatal development early stages. Thus, the animals’ live weight with the bGH-AluIVV-bIGF-1-SnaBIBB diplotype at the age of 24 months exceeds the Aberdeen-Angus breed live weight standard by 45 kg (12%) and the total sample - by 12.52 kg (3%). The bGH-AluILL-bIGF-1-SnaBIAA diplotype score is 2.93% higher than the total sample. The mass  index average value of animals with the bGH-AluILV-bGHR-SspIFY diplotype at 18 months is 3.98% lower than the total sample. In animals with the bGHR-SspIFF-bIGF-1-SnaBIBB diplotype at the age of 24 months, the churn index value is lower than the total sample by 3.74%. Thus, the diplotypes bGH-AluIVV-bIGF-1-SnaBIBB and bGH-AluILL-bIGF-1-SnaBIAA can be considered genetic markers of increased meat productivity and the diplotypes bGH-AluILV-bGHR-SspIFY and bGHR-SspIFF-bIGF-1-SnaBIBB-reduced meat productivity. The animals’ selection with diplotypes that increase meat productivity will reduce the investment period and increase the agricultural production profitability. For breeding activities, it is recommended to maintain the animals’ number with the diplotypes bGH-AluIVV-bIGF-1-SnaBIBB and bGH-AluILL-bIGF-1-SnaBIAA.},
journal = {OnLine Journal of Biological Sciences},
publisher = {Science Publications}
}