TY  - JOUR
AU  - Alghabban, Areej Jameel M. 
PY  - 2021
TI  - The Effects of Costus Root Aqueous Extract against Schistosomiasis, Liver Damage and Oxidants in Mouse Models of Schistosoma mansoni Infection
JF  - OnLine Journal of Biological Sciences
VL  - 21
IS  - 2
DO  - 10.3844/ojbsci.2021.207.216
UR  - https://thescipub.com/abstract/ojbsci.2021.207.216
AB  - Schistosomiasis is one of the major human parasitic diseases in many developing countries that causing chronic ill health in humans. The present work aimed to study the possible curative role of Costus (Saussurea lappa) root extract against Schistosoma mansoni infection induced liver toxicity, cytokines, oxidative stress and DNA damage in mice. 40 adult male micewere divided into four groups (G1, control; G2, Costus; G3, infection with S. mansoni live cercariae; G4, S. mansoni infection followed by Costus treatment). By comparison to control, mice with S. mansoni infection exhibited significantly (p