@article {10.3844/ojbsci.2021.207.216, article_type = {journal}, title = {The Effects of Costus Root Aqueous Extract against Schistosomiasis, Liver Damage and Oxidants in Mouse Models of Schistosoma mansoni Infection}, author = {Alghabban, Areej Jameel M.}, volume = {21}, number = {2}, year = {2021}, month = {Apr}, pages = {207-216}, doi = {10.3844/ojbsci.2021.207.216}, url = {https://thescipub.com/abstract/ojbsci.2021.207.216}, abstract = {Schistosomiasis is one of the major human parasitic diseases in many developing countries that causing chronic ill health in humans. The present work aimed to study the possible curative role of Costus (Saussurea lappa) root extract against Schistosoma mansoni infection induced liver toxicity, cytokines, oxidative stress and DNA damage in mice. 40 adult male micewere divided into four groups (G1, control; G2, Costus; G3, infection with S. mansoni live cercariae; G4, S. mansoni infection followed by Costus treatment). By comparison to control, mice with S. mansoni infection exhibited significantly (p}, journal = {OnLine Journal of Biological Sciences}, publisher = {Science Publications} }