TY - JOUR AU - Djerrou, Zouhir AU - Maameri, Zineb AU - Halmi, Sihem AU - Djaalab, Hadria AU - Riachi, Foulla AU - Benmaiza, Loubna AU - Hamdipacha, Youcef PY - 2015 TI - Hepatoprotective Effect of Opuntia Ficus-Indica Aqueous Extract against Carbon Tetrachloride-Induced Toxicity in Rats JF - OnLine Journal of Biological Sciences VL - 15 IS - 2 DO - 10.3844/ojbsci.2015.36.41 UR - https://thescipub.com/abstract/ojbsci.2015.36.41 AB - The present study was undertaken to evaluate the hepatoprotective activity of Opuntia ficus-indicaL. aqueous extract. About 24 Wistar male rats were divided randomly to 4 groups of 6 each. The 1st was given distilled water and served as normal control (CRL). The 2nd was intoxicated orally with carbon tetrachloride at a dose of 1.5 mL/kg each 72 h (CCl4 group) for a period of 15 days. 2 other groups were intoxicated as CCl4 group and treated once daily by aqueous extract of Opuntiaficus-indica L. at doses of 2 mL/kg or 5 mL/kg respectively (OFI1 and OFI2 groups). The results showed a significant elevation of Aspartate Amino Transferase (AST) (ANOVA, p