@article {10.3844/ojbsci.2010.109.113,
article_type = {journal},
title = {Susceptibility of Candida Species Isolated From HIV Infected and Newborn Candidaemia Patients to Amphotericin B},
author = {Basu, Saikat and Chakraborty, Debasrita and Das, Satadal},
volume = {10},
number = {2},
year = {2010},
month = {Jun},
pages = {109-113},
doi = {10.3844/ojbsci.2010.109.113},
url = {https://thescipub.com/abstract/ojbsci.2010.109.113},
abstract = {Problem statement: HIV infected and neonatal candidaemia is a serious condition where proper selection of the antifungal agent is the key factor in the prognosis of the disease. Thus in this study susceptibility of Candida species to Amphotericin B was explored in such patients. Approach: Forty different Candida isolates obtained from blood culture of such candidaemia cases were tested for Amphotericin B susceptibility by disc diffusion method and by microdilution method. Results: There was a good correlation between low MIC values and large inhibition zones among most isolates as expected, particularly with 24 h reading. Several outlier data were also observed during the study. After analysis it was found that 24 h microdilution method results were better for interpretation of susceptibility results. Conclusion: Microdilution method is the reliable method for susceptibility testing of Candida isolates from HIV infected and neonatal candidaemia patients to Amphotericin B.},
journal = {OnLine Journal of Biological Sciences},
publisher = {Science Publications}
}