@article {10.3844/ajptsp.2011.88.95,
article_type = {journal},
title = {Effect of Intrahippocampal γ Aminobutyrate B Receptor on Pain Sensitivity during Estrous Cycle},
author = {Taherianfard, Mahnaz and Ghorbani, Rohollah},
volume = {6},
year = {2011},
month = {Nov},
pages = {88-95},
doi = {10.3844/ajptsp.2011.88.95},
url = {https://thescipub.com/abstract/ajptsp.2011.88.95},
abstract = {Problem statement: There is a relationship between sexual hormones and pain sensitivity and also a role for hippocampal GABAB receptor in nociception. Therefore, the aim of the present investigation was to evaluate the effect of intrahippocampal injection of GABAB receptor agonist (baclofen) and GABAB receptor antagonist (CGP35348) on pain sensitivity during the estrous cycle. Approach: Forty eight adult female rats were used. The animals were divided into four groups: (1) Control; (2) Sham; (3) Baclofen 4.25 or 8.54 μg rat-1; (4) CGP35348 alone with doses 3 or 5 μg rat-1 and (5) CGP35348 3 or 5 μg rat-1 after 0.75 μL of baclofen 8.54 μg rat-1. Data were analyzed by two ways ANOVA measuring. The level of significance was p},
journal = {American Journal of Pharmacology and Toxicology},
publisher = {Science Publications}
}