@article {10.3844/ajptsp.2007.106.110, article_type = {journal}, title = {Anti-hyperglycaemic and Anti-obesity Effects of Capparis spinosa and Chamaemelum nobile Aqueous Extracts in HFD Mice}, author = {Lemhadri, A. and Eddouks, Mohamed and Sulpice, Thierry and Burcelin, Remy}, volume = {2}, year = {2007}, month = {Sep}, pages = {106-110}, doi = {10.3844/ajptsp.2007.106.110}, url = {https://thescipub.com/abstract/ajptsp.2007.106.110}, abstract = {This study was undertaken in order to evaluate the possible anti-hyperglycaemic and body weight reducing activities of the aqueous extract of both Capparis spinosa (CS) and Chamaemelum nobile (CN) (20 mg/kg-1). The results demonstrate clearly that repeated oral administration of both CS and CN aqueous extract evoked a potent anti-hyperglycaemic activity in high fat diet (HFD) obese mice. Postprandial hyperglycaemic peaks were significantly lower in plant-treated experimental groups. In other hand, body weight was significantly lower in CS and CN-treated groups when compared to the control one after daily oral administration of CS and CN aqueous extracts for 15 days. We can conclude that these plants evoked potent anti-hyperglycaemic and anti-obesity effects. This fact could support their use by the Moroccan population for diabetes control and treatment.}, journal = {American Journal of Pharmacology and Toxicology}, publisher = {Science Publications} }