@article {10.3844/ajisp.2017.186.193, article_type = {journal}, title = {Chronic Mental Stress Induces Reversible Reduction of Natural Killer Cells and CD56dim Subpopulation}, author = {Ismail, Manar M.}, volume = {13}, year = {2017}, month = {Aug}, pages = {186-193}, doi = {10.3844/ajisp.2017.186.193}, url = {https://thescipub.com/abstract/ajisp.2017.186.193}, abstract = {Generally, studying to be a health care provider is a stressful and demanding field and the students have to face many stressors that may affect their general health status including the immune system. This work aimed at studying the effect of prolonged naturalistic life-stress exposure on the percentage of peripheral blood T-lymphocytes and Natural Killer (NK) cells in female laboratory medicine students. 52 peripheral blood samples in the last week of the final written exam (stress time point) and 27 samples after 12 weeks rest (control) were withdrawn and analyzed by flow cytometry. At the stress time point, there was a significant high T helper cells percentage with elevation of T helper/T cytotoxic ratio, P value }, journal = {American Journal of Immunology}, publisher = {Science Publications} }