TY - JOUR AU - Josef, Richter AU - Vladimir, Svozil AU - Vlastimil, Král AU - Lucie, Rajnohová Dobiášová AU - Ivana, Stiborová AU - Jitka, Pohořská AU - Vaclav, Vetvicka PY - 2015 TI - Effects of Dietary Nucleotides on Immune Mechanisms and Physical State in Children with Chronic Respiratory Problems JF - American Journal of Immunology VL - 11 IS - 2 DO - 10.3844/ajisp.2015.26.32 UR - https://thescipub.com/abstract/ajisp.2015.26.32 AB - Heavy industrial pollution and/or passive smoking negatively affect the overall immune health of a population. We used a model of children with chronic respiratory problems and evaluated the effects of short term supplementation of their diet with nucleotides. We measured the level of sIgA, eNO levels and total physical activity. We found positive effects of oral supplementation with commercially available nucleotides. Our data demonstrate strong improvements in physical activity, strong decrease of eNO levels and maintaining of the levels of sIgA. We conclude that supplementation with nucleotides offers an easy way to improve health conditions in children.