@article {10.3844/ajisp.2013.43.47, article_type = {journal}, title = {Placebo-Driven Clinical Trials of Transfer Point Glucan #300 in Children with Chronic Respiratory Problems: Antibody Production}, author = {Vaclav, Vetvicka and Josef, Richter and Vladimir, Svozil and Lucie, Rajnohova Dobiasova and Vlastimil, Kral}, volume = {9}, year = {2013}, month = {Jun}, pages = {43-47}, doi = {10.3844/ajisp.2013.43.47}, url = {https://thescipub.com/abstract/ajisp.2013.43.47}, abstract = {The role of glucan in stimulation of immune reactions has been well-established. In this report, we focused on the antibody production in glucan-supplemented children with chronic respiratory problems. We measured the levels of salivary IgA, IgM and IgG in 40 children aged 8-12 years and evaluated the effects of 100 mg d-1 oral dose of glucan. We found a significant increase in production of all tested antibodies in the glucan-stimulated group, but a decrease of antibody production in the control group. A thirty-day oral application of yeast-based natural immunomodulator β-glucan strongly stimulated the mucosal immunity of children with chronic respiratory problems.}, journal = {American Journal of Immunology}, publisher = {Science Publications} }