TY  - JOUR
AU  - Jahromi, Abdolreza Sotoodeh 
AU  - Shojaei, Mohammad 
AU  - Farjam, Mohammad Reza 
AU  - Madani, Abdolhossien 
PY  - 2013
TI  - Association of Anti-Phosphatidylcholine Antibodies with Acute Myocardial Infarction: A Comparative Study
JF  - American Journal of Immunology
VL  - 9
IS  - 4
DO  - 10.3844/ajisp.2013.116.119
UR  - https://thescipub.com/abstract/ajisp.2013.116.119
AB  - Many factors play a role in Acute Myocardial Infarction (AMI). One those anti-Phospholipid (aPL) antibodies, that may act in the induction of immunological response leading to the development of AMI. Anti-Phosphatidylcholines (PC) antibody is detected in various diseases like rheumatoid arthritis, systemic lupus erythematosus and anti-phospholipid antibody syndrome. The study of anti-PC antibody in AMI might shed light on etiologic mechanisms in the pathogenesis of acute coronary syndromes. This study was designed to investigate whether prevalence of anti-PC antibodies, in patients who had AMI and to analyze their relationship with traditional cardiovascular risk factors. The prevalence of anti-PC IgG and IgM in a well characterized group of patients with AMI as a case group and in age and sex matched healthy subjects as control group. Sera from the case and the control groups were tested to evaluate the presence of IgG and IgM isotypes to anti-PC by ELISA method. The prevalence of anti-PC IgG and also IgM in the case group resulted significantly higher than in the control group with AMI (p