TY - JOUR AU - Beatty, Robert Michael PY - 2023 TI - Long COVID-19 Symptoms Remedied by Anti-Viral Treatment in Neurosurgical Patients JF - American Journal of Infectious Diseases VL - 19 IS - 3 DO - 10.3844/ajidsp.2023.39.44 UR - https://thescipub.com/abstract/ajidsp.2023.39.44 AB - The pandemic of COVID-19 is the largest in this century. Aside from the acute infection, some of the patients have been challenged with a complication that is known as long COVID-19. The symptoms of long COVID-19 are extensive and diverse. Long COVID-19 continues to plague many patients post-COVID-19 infection. No universal treatment has been found. This study presents four patients who suffered from long COVID-19. Each patient presented with a different and diverse symptom of long COVID-19. Each of the patient's symptoms resolved or greatly improved upon taking the anti-viral drug acyclovir. Acyclovir has been in use since 1981 and is generally considered safe. A novel theory as to the pathophysiology of long COVID-19 symptoms and the result of a new treatment is presented. The purpose of this study is to provide a foundation for much bigger studies and useful resources for further testing to halt long COVID-19.