@article {10.3844/ajidsp.2020.85.88,
article_type = {journal},
title = {Evaluation of A Rapid IgM-IgG Combined Antibody Test for SARS-CoV-2 Infection: Single Italian Center Study},
author = {Margiotti, Katia and Cupellaro, Marina and Emili, Sabrina and Mesoraca, Alvaro and Giorlandino, Claudio},
volume = {16},
number = {2},
year = {2020},
month = {Jun},
pages = {85-88},
doi = {10.3844/ajidsp.2020.85.88},
url = {https://thescipub.com/abstract/ajidsp.2020.85.88},
abstract = {The need for timely establishment of diagnostic assays of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is demanded in laboratories worldwide. We evaluated the performance of a flow immunoassay which can detect IgM an IgG antibodies simultaneously against SARS-CoV-2 virus in human blood within 15 min. Among the 132 positive novel Coronavirus Disease 19 (COVID-19) cases, 126 tests were consistent with previous quantitative Real Time PCR (qRT-PCR) assays. Among the 62 negative cases, 60 were consistent with qRT-PCR assays except for 2 cases. In this study, 2019-nCOV/COVID-19 IgG/IgM Rapid Test Device showed 95.5% sensitivity and 96.8% specificity. In conclusion, Rapid IgM-IgG Combined Antibody Test showed high detection consistency among all analysed samples. Suggesting that could be used for the rapid screening of SARS-CoV-2 carriers, either symptomatic or asymptomatic.},
journal = {American Journal of Infectious Diseases},
publisher = {Science Publications}
}