TY - JOUR AU - Edmond, Tchiakpe AU - Yehouenou, Laurence Carine AU - Malick, Zahra Fall AU - Arsène, Kpangon Amadohoué AU - René, Keke Kpemahouton AU - Malick Diouara, Abou Abdallah AU - Tondé, Issa AU - Bankolé, Honoré Sourou AU - Wilfried, Bekou Kossi AU - Marius, Esse Atchéni AU - Ndiaye, Halimatou Diop AU - Kane, Coumba Touré PY - 2017 TI - Antimicrobial Susceptibility of Community Acquired Escherichia coli in Urinary Tract Infections (UTI) in Benin for Eleven Years (2005-2015) JF - American Journal of Infectious Diseases VL - 13 IS - 2 DO - 10.3844/ajidsp.2017.21.27 UR - https://thescipub.com/abstract/ajidsp.2017.21.27 AB - Antimicrobial resistance became a growing public health problem in the world and Escherichia coli (E. coli) appeared as one of nine bacteria commonly causing infections in community and hospitals. It prevalence and it resistance to antibiotics were evaluated in Benin throughout an eleven year period. In this retrospective study, routine urine samples from patients collected at the National Laboratory (NL) of Health Ministry during the period 2005-2015 were analyzed. Samples higher than 103 CFU/mL bacterial growth were considered positive and for these cases, the bacteria were identified and Antimicrobial Susceptibility Test (AST) was performed. From the 4467 samples analyzed, 1455 (32.6%) were positive with E. coli preponderance (38.3%) of all isolated germs and (58.5%) of enterobacteriaceae. Most of the isolates were susceptibility to netilmicin (80%), gentamycin (93%), chloramphenicol (70%), pipemidic acid (60%), nalidixic acid (75%), ciprofloxacin (75%), amoxicillin/clavulanic acid (80%) and nitrofurantoin (100%). Susceptibility rates increased for cefotaxim (78-100%), ceftriaxon (71-100%) and aztreonam (67-100%). Resistances were observed for minocyclin (70%), Trimethoprim/Sulfamethoxazole (TMP-SMX) (60%), ampicillin (67%), amoxicillin (75%), carbenicillin (86%), cephalothin and cephalexin (50 and 80% respectively). The use of drugs such as minocyclin, ampicillin, amoxicillin, carbenicillin, cephalothin, cephalexin and trimethoprim/sulfamethoxazole does not seem appropriate for empirical treatment of UTI in Benin.