TY - JOUR AU - Liu, Ching-Chuan AU - Huang, Kao-Jean AU - Huang, Mei-Chih AU - Lin, J.-J. AU - Wang, S.-M. AU - Liu, Jen-Jou AU - Tsai, Jih-Jin AU - Huang, Jyh-Hsiung AU - Lin, Yee-Shin AU - Liu, Hsiao-Sheng AU - Yeh, Trai-Ming AU - Lei, Huan-Yao PY - 2008 TI - High Case-Fatality Rate of Adults With Dengue Hemorrhagic Fever During An Outbreak In Non-Endemic Taiwan: Risk Factors For Dengue-Infected Elders JF - American Journal of Infectious Diseases VL - 4 IS - 1 DO - 10.3844/ajidsp.2008.10.17 UR - https://thescipub.com/abstract/ajidsp.2008.10.17 AB - In 2002, a dengue outbreak occurred in Taiwan with 5336 confirmed cases, 242 DHF and 21 death, the case fatality rate reached 8.7% (21/242). The demographic data of these age-specific dengue patients showed that dengue virus infection caused symptom primarily occurred in adults. A comparative analysis of clinical and laboratory data for DF, DHF/DSS and fatal DSS found that high fatality from dengue infection was associated with the following patient conditions: (1) age above 55 years, (2) underlying diseases with hypertension, chronic renal insufficiency, or diabetes, (3) abnormal thrombocytopenia, APTT and PT prolongation, low hematocrit (