@article {10.3844/ajidsp.2007.42.50, article_type = {journal}, title = {Evaluation of Acute-phase Reactants, Immunologic Markers and other Clinical and Laboratory Parameters in Patients with Pneumonia and Non-pneumonic Lower Respiratory Tract Infections}, author = {Collazos, Julio and Martínez, María del Mar and Izquierdo, Fernando}, volume = {3}, number = {1}, year = {2007}, month = {Mar}, pages = {42-50}, doi = {10.3844/ajidsp.2007.42.50}, url = {https://thescipub.com/abstract/ajidsp.2007.42.50}, abstract = {More efficacious tools to distinguish pneumonia from other acute lower respiratory tract infections (OALRTI) in facilities where radiologic studies are not easily or rapidly available are desirable to select the patients who should undergo chest radiographs, to avoid unnecessary visits to the emergency wards of hospitals and to optimize health resources. To this end we analyzed the relevance of many clinical and laboratory parameters, including acute-phase reactants and immune activation markers, in 98 patients with pneumonia and 149 with OALRTI seen at the emergency ward of our hospital. Many clinical and laboratory parameters were associated with the diagnosis of pneumonia in the univariate analysis. Among them, C-reactive protein proved to be the most discriminant for the differentiation between the two conditions (area under the ROC curve 0.83, 95%CI 0.78-0.89, P}, journal = {American Journal of Infectious Diseases}, publisher = {Science Publications} }