@article {10.3844/ajidsp.2007.195.201,
article_type = {journal},
title = {Nutritional control of HIV-AIDS-A case for Selenium},
author = {Kalantari, Parisa and Vunta, Hema and Palempalli, Umamaheswari D. and Reddy, C. Channa and Henderson, Andrew J. and Prabhu, K. Sandeep},
volume = {3},
number = {4},
year = {2007},
month = {Dec},
pages = {195-201},
doi = {10.3844/ajidsp.2007.195.201},
url = {https://thescipub.com/abstract/ajidsp.2007.195.201},
abstract = {Selenium (Se) is a micronutrient that is incorporated into proteins. Some of the selenoenzymes such as GPXs and thioredoxin reductases exhibit glutathione peroxidase-dependent activities towards organic and inorganic peroxides. Thus, selenoenzymes play a pivotal role in mitigating oxidative stress caused by accumulation of peroxides. In this respect, selenoproteins may interfere with the transcription-driven by oxidative stress-dependent signaling mechanisms to influence the expression of redox sensitive genes, including inflammatory cytokines and HIV provirus. Several epidemiological studies support our view that Se supplementation affects transcription of HIV; however, the underlying mechanism is not elucidated. In this mini review, we consider the relationship between Se and HIV and propose possible mechanisms by which Se controls HIV transcription.},
journal = {American Journal of Infectious Diseases},
publisher = {Science Publications}
}