@article {10.3844/ajbsp.2019.14.17, article_type = {journal}, title = {Comparison of IncL/M Plasmids Using the Neighbor-Joining Method on Basis repA and excA Genes}, author = {Abdelaziz, Touati and Assia, Mairi}, volume = {8}, year = {2020}, month = {Feb}, pages = {14-17}, doi = {10.3844/ajbsp.2019.14.17}, url = {https://thescipub.com/abstract/ajbsp.2019.14.17}, abstract = {The aim of this study is to make comparison of IncL/M groups on basis of two genes candidates’ repA and excA genes. The sequences of 27 plasmids were compared using the neighbor-joining method. This method was used to construct a phylogenetic tree for the nucleotide sequences of two genes (repA and excA), using the program MEGA X software. The evolutionary distances were computed using the maximum composite likelihood method. The neighbor-joining method analysis showed different results based on the gene used for comparison. The repA gene was more accurate than excA gene to distinguish between different incL/M plasmids. This study suggested that IncL/M plasmids harboring different antibiotic resistance genes have evolved differently.}, journal = {Current Research in Bioinformatics}, publisher = {Science Publications} }