@article {10.3844/ajbbsp.2010.19.24,
article_type = {journal},
title = {Do Resistin and Tumor Necrosis Factor-α Relate to Changes in Insulin Resistance in Normal Pregnancy?},
author = {Zareian, Parvin and Jahromi, Abdolreza Sotoodeh and Rad, Fateme Hemati and Zarei, Safar},
volume = {6},
number = {1},
year = {2010},
month = {Mar},
pages = {19-24},
doi = {10.3844/ajbbsp.2010.19.24},
url = {https://thescipub.com/abstract/ajbbsp.2010.19.24},
abstract = {Problem statement: The purpose of this study was to evaluate the role of resistin and Tumor Necrosis Factor-α (TNF-α) in insulin resistance during pregnancy. Approach: Serum resistin and TNF-α concentrations were measured by ELISA in 86 healthy pregnant women (26, 23 and 37 of them in the 1st, 2nd and 3rd trimesters, respectively) and in 21 healthy non pregnant women in a cross sectional study. Results: Resistin concentration was significantly higher in the third trimester (9.5±3.3 ng mL-1) as compared with non pregnant women (7±3.3 ng mL-1). Serum TNF-α level were also significantly increase in pregnant women (2.6±1.9 pg mL-1) as compared with maternal healthy controls (0.8 ±0.7 pg mL-1). There were significant correlation between gestational age and BMI (r = 0.28, p = 0.01), resistin (r = 0.36, p = 0.002) and TNF-α (r = -0.44, p},
journal = {American Journal of Biochemistry and Biotechnology},
publisher = {Science Publications}
}