@article {10.3844/ajbbsp.2006.9.18, article_type = {journal}, title = {The Meaning of a Redundant Codon: There is Protein Folding Information in Nucleic Acids in Addition to the Genetic Code}, author = {Biro, Jan C. and Biro, Josephine M.K.}, volume = {2}, number = {1}, year = {2006}, month = {Mar}, pages = {9-18}, doi = {10.3844/ajbbsp.2006.9.18}, url = {https://thescipub.com/abstract/ajbbsp.2006.9.18}, abstract = {All the information necessary for protein folding is supposed to be present in the amino acid sequence. It is still not possible to provide specific ab initio structure predictions by bioinformatical methods. It is suspected that additional folding information is present in protein coding nucleic acid sequences, which is not represented by the known genetic code. Nucleic acid subsequences comprising the 1st and/or 3rd codon residues in mRNAs express significantly higher free folding energy (FFE) than the subsequence containing only the 2nd residues (p}, journal = {American Journal of Biochemistry and Biotechnology}, publisher = {Science Publications} }