@article {10.3844/ajbbsp.2006.154.160, article_type = {journal}, title = {Hypoglycemic and Antihyperlipidemic Effect of Four Korean Medicinal Plants in Alloxan Induced Diabetic Rats}, author = {Kim, Ji Su and Ju, Jung Bong and Choi, Chang Won and Kim, Sei Chang}, volume = {2}, number = {4}, year = {2006}, month = {Dec}, pages = {154-160}, doi = {10.3844/ajbbsp.2006.154.160}, url = {https://thescipub.com/abstract/ajbbsp.2006.154.160}, abstract = {To consider potentially new hypoglycemic and antihyperlipidemic sources, aqueous extracts from four Korean medicinal plants, Chrysanthemum coronarium, Dioscorea batatas, Morus alba, Citrus unshiu, were investigated in alloxan-induced diabetic rats. To induce diabetes, 36 rats were administered alloxan orally (120 mg/kg body weight) for 2 weeks and among those 6 rats were used as a diabetic control. Effect of extracts from four medicinal plants on blood glucose levels of diabetic rats was determined at various time interval for 9 h after oral administration of the first extract at 100 mg dose /kg body weight. In addition, GOT, GPT, LDH, total cholesterol (TC) and triglyceride (TG) were determined 7 days after daily oral administration of each extract. The glucose levels of diabetic rats treated with C. coronarium and M. alba were significantly decreased, respectively, at 3 h and 5 h after administration (p}, journal = {American Journal of Biochemistry and Biotechnology}, publisher = {Science Publications} }