TY  - JOUR
AU  - Ventsova, Inna 
AU  - Safonov, Vladimir 
PY  - 2021
TI  - The Role of Oxidative Stress during Pregnancy on Obstetric Pathology Development in High-Yielding Dairy Cows
JF  - American Journal of Animal and Veterinary Sciences
VL  - 16
IS  - 1
DO  - 10.3844/ajavsp.2021.7.14
UR  - https://thescipub.com/abstract/ajavsp.2021.7.14
AB  - The study aimed to examine the processes of oxidative stress and their intensity depending on the state of the antioxidant system in dairy cows. The study was conducted in 2018-2019 on the territory of the Druzhba breeding factory (Voronezh region, Russia) and involved 154 cows divided into 4 groups. Group 1 consisted of healthy animals (n = 83). Group 2 contained animals with afterbirth retention (n = 6). Group 3 included animals with uterine subinvolution (n = 49). Group 4 comprised animals with postpartum catarrhal-purulent endometritis (n = 16). The blood samples were taken from the animals to estimate the content of vitamin E, lipids, malonic aldehyde and enzymes-catalases, reductase and ferroxidase. The concentration of vitamin E in groups 1 and 4 were found to decrease (by 3.9-23.2%; 30.7±2.16-25.9±2.16 compared to 31.9±1.68 μM/L) within two months. The level of malonic aldehyde in group 4 was higher than in other groups after the first month. In one month, its level increased by 20.6% (1.11±0.09 μM/L) by 35.4, 19.4 and 6.7%, respectively (P<0.01-0.001). The exhibited differences indicate the strong significance of functional insufficiency of the antioxidant protection system during the development of oxidative stress during pregnancy and, as a result, the etiology and pathogenesis of parturient and postpartum complications in cows.