TY  - JOUR
AU  - Haas, Melanie 
AU  - Kaup, Franz-Josef 
AU  - Neumann, Stephan 
PY  - 2015
TI  - Evaluation of Serum Interleukin-8 (CXCL8) Concentrations in Tumor Bearing Dogs
JF  - American Journal of Animal and Veterinary Sciences
VL  - 10
IS  - 4
DO  - 10.3844/ajavsp.2015.202.211
UR  - https://thescipub.com/abstract/ajavsp.2015.202.211
AB  - Interleukin-8 (IL-8 or CXCL8) is a pro-inflammatory and angiogenic chemokine involved in tumorigenesis. Serum CXCL8 is elevated in various neoplastic diseases, but its potential value as a tumor marker in veterinary medicine is unknown. Here, we measured serum CXCL8 concentrations in dogs with various neoplastic diseases using a commercially available canine ELISA kit and analyzed its relationship with patient and disease features. Serum CXCL8 was detected in significantly higher concentrations in tumor bearing dogs compared with healthy patients (p