TY  - JOUR
AU  - Khayatnouri, Mirhadi 
AU  - Safavi, Seyed Esmail 
AU  - Safarmashaei, Saied 
AU  - Mikailpourardabili, Behrouz 
AU  - Babazadeh, Daryoush 
PY  - 2012
TI  - Effect of Saffron on Histomorphometric Changes of Testicular Tissue in Rat
JF  - American Journal of Animal and Veterinary Sciences
VL  - 6
IS  - 4
DO  - 10.3844/ajavsp.2011.153.159
UR  - https://thescipub.com/abstract/ajavsp.2011.153.159
AB  - Problem statement: Saffron is widely used as a food flavor and has well known medicinal effects. This drug has an effect on steroid and sexual hormones. The aim of this study was investigation of Saffron orally administration on histomorphometric change of testicular tissue in rat. In this experimental study, 40 male rats are used (4 groups and 10 rats in each group). Approach: Animals were received Saffron (50, 100 and 200 mg kg-1) daily orally administration, during 28 days. As one group was control (normal saline) and three groups was drug consumer. The testis tissue was sampled after passing of above time and section providing, was stained by H and E. Results: The histomorphometric changes of testicular tissue which include, seminiferous tubules diameter, seminiferous epithelial thickness, interstitial tissue and testicular capsule thickness were studied. Results showed that seminiferous tubules diameter, seminiferous epithelial thickness had significantly decreased (p