Literature Review Open Access

The Anti-Nociceptive/Anti-Inflammatory Actions of Botulinum Toxin A for the Treatment of Chronic Pain; A Literature Review

Racha Hajj1 and Camille Haddad1
  • 1 Saint-Joseph University, Lebanon

Abstract

The aim of this article is to describe the new actions of botulinum toxin A for chronic pain treatment. BT/A inhibits the exocytosis of synaptic vesicles containing the pain mediators neurotransmitters, reduces the post traumatic trigeminal neuralgia pain, inhibits the release of microglia derived TNF-α as well as other pro inflammatory cytokines, viable treatment option in the case of patients who do not respond to conservative treatment methods of chronic pain (medication) BT/A is an emerging treatment for chronic pain; patients with severe chronic facial pain, not responding to conventional treatments, can respond to botulinum type a injections

Current Research in Dentistry
Volume 12 No. 1, 2021, 62-70

DOI: https://doi.org/10.3844/crdsp.2021.62.70

Submitted On: 5 June 2021 Published On: 10 August 2021

How to Cite: Hajj, R. & Haddad, C. (2021). The Anti-Nociceptive/Anti-Inflammatory Actions of Botulinum Toxin A for the Treatment of Chronic Pain; A Literature Review. Current Research in Dentistry, 12(1), 62-70. https://doi.org/10.3844/crdsp.2021.62.70

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Keywords

  • Anti Inflamatory
  • Anti Nociceptive
  • BiTox/AA
  • Botulinum Toxin A
  • Chronic Pain
  • Derm-BOT