Research Article Open Access

Seroprevalence of SARS-CoV-2 Antibodies and Associated Factors Among Health Care Workers at the Departmental and Teaching Hospital of Borgou (Republic of Benin) in 2022

Cossi Angelo Attinsounon1,2, Alidjinou Kazali2, Vodounou Amos1, Acakpo Jocelyn1 and Dovonou Albert1,2
  • 1 Department of Medicine and Medical Specialties, Faculty of Medicine, University of Parakou, Benin
  • 2 Department of Internal Medicine, Faculty of Medicine, University of Parakou, Benin

Abstract

COVID-19 is a contagious viral infection, responsible for a pandemic that started in China in December 2019. Health Care Workers (HCWs) have been particularly exposed to this virus. The aim of this study was to estimate the seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibodies and predictors among health care workers at the Departmental and Teaching Hospital of Borgou (DTH-B). This was a descriptive and analytical cross-sectional study conducted from June 27 to July 27, 2022. Participants were recruited using a simple random draw from the list of HCWs in each hospital department. All participants gave free and informed oral consent to participate in the survey. A pre-established questionnaire was used to collect epidemiological and clinical data. Each participant received a rapid screening test for SARS-CoV-2 antibodies (Immunoglobulin [Ig] G and M). STATA/MP 14.1 software was used for data analysis. A total of 139 HCWs participated in the survey. The sex ratio was 0.51 and the mean age was 40.48±9.12 years. The SARS-CoV-2 antibodies seroprevalence was 92.02%. Eighty-six participants (63.70%) had received a complete COVID-19 vaccination and 135 (97.12%) had received at least one dose of one of the available COVID-19 vaccines in Benin. A history of confirmed COVID-19 was recorded in 31 participants (22.30%). Hospital exposure of confirmed COVID-19 cases was noted in 104 (74.82%) participants. Family exposure was noted in 18 (12.95%) participants. Factors significantly associated with SARS-CoV-2 antibodies positivity in multivariate analysis were female gender (p = 0.001) and complete vaccination against COVID-19 (p = 0.002). The SARS-CoV-2 antibodies seroprevalence among HCWs was as high as the vaccination coverage in the departmental and teaching hospital at Borgou. It would reflect the joint effect of significant exposure to the virus and the effectiveness of the COVID-19 vaccines.

American Journal of Infectious Diseases
Volume 19 No. 2, 2023, 28-38

DOI: https://doi.org/10.3844/ajidsp.2023.28.38

Submitted On: 28 January 2023 Published On: 26 April 2023

How to Cite: Attinsounon, C. A., Kazali, A., Amos, V., Jocelyn, A. & Albert, D. (2023). Seroprevalence of SARS-CoV-2 Antibodies and Associated Factors Among Health Care Workers at the Departmental and Teaching Hospital of Borgou (Republic of Benin) in 2022. American Journal of Infectious Diseases, 19(2), 28-38. https://doi.org/10.3844/ajidsp.2023.28.38

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Keywords

  • SARS-CoV-2
  • Antibodies
  • Seroprevalence
  • Health Care Workers
  • Borgou
  • Benin