Case Report Open Access

Disseminated Cryptococcal Disease with Skeletal and Pulmonary Involvement

Nikko Rowe Asuncion Tabliago1, Paula McKenzie2, Caroline Dillon3 and Amelia Morgan4
  • 1 Department of Internal Medicine, Geisinger Medical Center, United States
  • 2 Department of Infectious Diseases, Geisinger Medical Center, United States
  • 3 Department of Pharmacy, Geisinger Medical Center, United States
  • 4 Department of Internal Medicine-Pediatrics, Geisinger Medical Center, United States

Abstract

Cryptococcus neoformans is an encapsulated yeast that typically causes illness in immunocompromised hosts. Manifestations of the disease include pulmonary, Central Nervous System (CNS), and rare skeletal involvement. Optimal antifungal therapy for skeletal involvement has yet to be established. Here we present a potential antifungal regimen for disseminated cryptococcal disease with skeletal and pulmonary involvement in a patient with Chronic Lymphocytic Leukemia (CLL) on ibrutinib therapy.

American Journal of Infectious Diseases
Volume 18 No. 3, 2022, 46-48

DOI: https://doi.org/10.3844/ajidsp.2022.46.48

Submitted On: 13 March 2022 Published On: 1 August 2022

How to Cite: Tabliago, N. R. A., McKenzie, P., Dillon, C. & Morgan, A. (2022). Disseminated Cryptococcal Disease with Skeletal and Pulmonary Involvement. American Journal of Infectious Diseases, 18(3), 46-48. https://doi.org/10.3844/ajidsp.2022.46.48

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Keywords

  • Cryptococcosis
  • Osteomyelitis
  • Fluconazole
  • Disseminated